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Glycocalyx scaffolding with synthetic nanoscale glycomaterials
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https://doi.org/10.1039/c7bm00289kAbstract
We report a method for programming complexity into the glycocalyx of live cells. Via a combination of glycomaterial synthesis and membrane remodeling, we have engineered cells to display native-like, mixed sialoglycan populations, while confining the activity of each glycan into a specific nanoscale presentation.
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