Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors
- Chang, Timothy S;
- Ding, Yi;
- Freund, Malika K;
- Johnson, Ruth;
- Schwarz, Tommer;
- Yabu, Julie M;
- Hazlett, Chad;
- Chiang, Jeffrey N;
- Wulf, David A;
- Group, UCLA Precision Health Data Discovery Repository Working;
- Antonio, Anna L;
- Ariannejad, Maryam;
- Badillo, Angela M;
- Balliu, Brunilda;
- Berkovich, Yael;
- Broudy, Michael;
- Dang, Tony;
- Denny, Chris;
- Eskin, Eleazar;
- Halperin, Eran;
- Hill, Brian L;
- Jain, Ankur;
- Katakwar, Vivek;
- Lajonchere, Clara;
- Magyar, Clara;
- Minton, Sheila;
- Mohammed, Ghouse;
- Muhamed, Ariff;
- Pavan, Pabba;
- Pfeffer, Michael A;
- Rakocz, Nadav;
- Rudas, Akos;
- Salonga, Rey;
- Sanders, Timothy J;
- Tung, Paul;
- Vu, Vu;
- Zheng, Ailsa;
- Geschwind, Daniel H;
- Butte, Manish J;
- Pasaniuc, Bogdan
- et al.
Published Web Location
https://www.sciencedirect.com/science/article/pii/S2589004221001565?via%3DihubAbstract
Coronavirus disease 2019 (COVID-19) has exposed health care disparities in minority groups including Hispanics/Latinxs (HL). Studies of COVID-19 risk factors for HL have relied on county-level data. We investigated COVID-19 risk factors in HL using individual-level, electronic health records in a Los Angeles health system between March 9, 2020, and August 31, 2020. Of 9,287 HL tested for SARS-CoV-2, 562 were positive. HL constituted an increasing percentage of all COVID-19 positive individuals as disease severity escalated. Multiple risk factors identified in Non-Hispanic/Latinx whites (NHL-W), like renal disease, also conveyed risk in HL. Pre-existing nonrheumatic mitral valve disorder was a risk factor for HL hospitalization but not for NHL-W COVID-19 or HL influenza hospitalization, suggesting it may be a specific HL COVID-19 risk. Admission laboratory values also suggested that HL presented with a greater inflammatory response. COVID-19 risk factors for HL can help guide equitable government policies and identify at-risk populations.
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